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by Ashok Sindhi
The removal of the black-box warning is more than a regulatory change, it’s a new beginning for women. A chance to: feel good again, sleep again, think clearly again, restore their libido, balance their metabolism, enjoy life without symptoms, and trust modern medicine.
And most importantly: A chance to stop being afraid of something that was never truly dangerous when used correctly.
This moment represents freedom: freedom from the myths, freedom from old research that terrified an entire generation, freedom from the idea that hormones were “dangerous,” “unnatural,” or only for women in extreme menopause.
For years, women avoided HRT because: They were told estrogen causes cancer, they believed testosterone would “make them manly,” they thought hormones caused weight gain, they were scared of blood clots, and they often felt doctors weren’t informed or confident enough.
All based on outdated studies that have been disproven for years. Now, women finally feel safe to ask questions, explore treatment, and improve their quality of life without fear or shame. This guide explains every type of HRT, plus the different medications and options available today to treat perimenopause, menopause, and hormonal imbalance.
What Exactly Is HRT?
Hormone Replacement Therapy replaces the hormones that your body naturally loses as you age, mainly estrogen, progesterone, and testosterone. When levels drop, symptoms appear. HRT restores balance so you can feel like yourself again.
The Different Types of HRT
Below are the main categories of hormone therapy. Every woman’s plan is personalized; there is no one-size-fits-all.
1. Estrogen Therapy
Used to treat hot flashes, night sweats, brain fog, dryness, and bone loss.
Forms: Pills, patches, creams, gels, vaginal tablets, vaginal ring, vaginal cream.
Specific medications may include: Estradiol, Estrace, Climara patch, Vivelle-Dot patch, Divigel, Premarin (older), Imvexxy, Yuvafem.
2. Progesterone Therapy
Protects the uterine lining and supports mood, sleep, and anxiety.
Forms: Oral progesterone (Prometrium — bioidentical), compounded progesterone creams, combination estrogen/progesterone pills.
Specific medications: Prometrium, compounded micronized progesterone, Bijuva (combo).
3. Testosterone Therapy for Women
Women need testosterone for mood, metabolism, libido, muscle tone, and energy.
Forms: Creams, gels, troches, pellets, low-dose injections.
Specific medications: Compounded testosterone cream, Testopel pellets (adjusted for women), testosterone cypionate micro-dosing.
4. Bioidentical Hormones
These have the same molecular structure as your natural hormones.
Forms include: capsules, creams, gels, troches, pellets.
Bioidentical options: Estradiol, progesterone, testosterone, DHEA, pregnenolone, and custom-compounded blends.
5. Pellet Therapy
Small pellets inserted under the skin that release hormones for 3–5 months.
Pellets can deliver: estrogen, testosterone, or combination therapy.
Popular brands: EvexiPEL (beBIONIC uses this), BioTE, SottoPelle.
Other Medications Used Alongside HRT
Not every woman needs the same medications. Today, there are dozens of options to support symptoms beyond hormones alone.
A. For Hot Flashes & Night Sweats
Besides estrogen, women may use:
- Veozah (fezolinetant) — non-hormonal, new, highly effective
- Paroxetine (Brisdelle) — low-dose SSRI
- Gabapentin — helps with nighttime symptoms
- Clonidine — for women who cannot take hormones
B. For Vaginal Dryness & Pain
Local estrogen is extremely effective and safe:
- Estradiol cream
- Estradiol vaginal tablets (Yuvafem/Imvexxy)
- Estring vaginal ring
- DHEA suppository (Intrarosa) for lubrication without estrogen
C. For Low Libido
Testosterone is #1, but other options include:
- Addyi (flibanserin) – daily tablet, increases desire
- Vyleesi (bremelanotide) – injection used before intimacy
D. For Mood, Sleep, Anxiety
Progesterone is a natural sleep aid. Other options include: low-dose SSRIs/SNRIs, magnesium, adaptogens, L-theanine, and compounded sleep blends.
E. For Weight Gain
Hormones affect metabolism, but women may combine HRT with: Semaglutide, Tirzepatide, Metformin, low-dose naltrexone (LDN), thyroid optimization.
F. For Thyroid Support
Options include: Levothyroxine (T4), Cytomel (T3), NP Thyroid / Armour Thyroid.
G. For Bone Health
Estrogen helps, but other medications may include: calcium + vitamin D, bisphosphonates, SERMs (Evista), parathyroid analogs.
How Do You Know Which Plan You Need?
When symptoms overlap, many women feel they need everything.
But that’s exactly why an experienced provider evaluates:
- your symptoms
- your labs
- your medical history
- your age
- your menstrual status
- your lifestyle
A personalized plan is always the safest and most effective.
If you’re in Tampa and curious about HRT, this is the ideal time to explore your options with a licensed, knowledgeable provider who understands women not outdated research or fear-based misconceptions.
Conclusion
At beBIONIC, our specialists create individualized HRT plans tailored to your biology, your symptoms, and your long-term health goals. We use evidence-based medicine, advanced lab testing, and modern therapies, including EvexiPEL pellets, to help women feel balanced, energized, and confident again.
If you’re ready to understand which HRT plan is right for you, schedule a consultation with beBIONIC today and take the next step toward feeling like yourself again.
